Use of direct oral anticoagulants for the prevention and treatment of thromboembolic disease in patients with reduced renal function: a short review of the clinical evidence
Kristine nyx 22 brush C Willett, Amanda M Morrill Department of Pharmacy Practice, School of Pharmacy, MCPHS University, Manchester, NH, USA Background: The use of direct oral anticoagulants (DOACs) is restricted by the limitations of clinical trials guiding therapy for patients with renal impairment, as many of these trials excluded patients with